Fostering healthy, happy
through proper physical
Why consider preconception care?
The role of early-life complications:
Taking into account maternal health prior to & during pregnancy seeks to decrease "early-life complications (ECLs) that is, potentially adverse events that occur during pregnancy and labor, at delivery, and early in neonatal life." 1
The role of epigenetics in pregnancy:
"The research showed that these genes are “turned on” in the placenta during complicated pregnancies and signal a placenta under duress.
Researchers found a prominent interaction between genes associated with risk for schizophrenia and a history of a potentially serious pregnancy complication.
Individuals having high genetic risk and serious early life complications have at least a 5x greater likelihood of developing schizophrenia in comparison to individuals with similarly high genetic risk but no history of serious obstetrical complications." 1
Optimal Health Functional Considerations:
1 Lieber Institute for Brain Development Press Release "Genes, Environment and Schizophrenia:
New Study Finds the Placenta is the Missing Link" Baltimore, MD. May 2018
2 Ursini, G., et al. "Convergence of placenta biology and genetic risk for schizophrenia" Nature
Medicine volume 24, pages 792–801, May 2018. DOI:10.1038/s41591-018-0021-y
3 Labrousse, V.F., et al. "Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory
deficits in mice exposed to lipopolysaccharide during gestation." Brain, Behavior, and Immunity, June 2018. DOI: 10.1016/j.bbi.2018.06.004
4 Ohm, J., Alcantara, J. "The Webster Technique: Definition, Application and Implications" International Chiropractic Pediatric Association.
5 Madore, C., et al. "Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota." Neural Plasticity Volume 2016, Article ID 3597209. DOI:10.1155/2016/3597209
6 Rossignol, D.A., Genuis. S.J., Frye, R.E. "Environmental toxicants and autism spectrum disorders: a systematic review." Translational Psychiatry volume 4, page e360 (2014) DOI: 10.1038/tp.2014.4
7 Lena Brundin et al. “Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression”. Brain, Behavior and Immunity doi:10.1016/j.bbi.2019.10.017.